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  1. In septic patients, hyperoxia may help with its bactericidal effects, but it may cause systemic impairments. The role of hyperoxia and the appropriate oxygen target in these patients is unknown. The aim of thi...

    Authors: Francesca Romana Catalanotto, Mariachiara Ippolito, Alice Mirasola, Giulia Catalisano, Marta Milazzo, Antonino Giarratano and Andrea Cortegiani
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2023 3:12
    Content type: Review Published on:

  2. Antimicrobial resistance represents a major critical issue for the management of the critically ill patients hospitalized in the intensive care unit (ICU), since infections by multidrug-resistant bacteria are ...

    Authors: Andrea Cortegiani, Massimo Antonelli, Marco Falcone, Antonino Giarratano, Massimo Girardis, Marc Leone, Federico Pea, Stefania Stefani, Bruno Viaggi and Pierluigi Viale
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2023 3:11
    Content type: Original Article Published on:

  3. Increasing evidence has associated positive fluid balance of critically ill patients with poor outcomes. The aim of this study was to explore the pattern of daily fluid balances and their association with outc...

    Authors: Chiara Robino, Guido Toncelli, Laura Arianna Sorrentino, Antonio Fioccola, Brigida Tedesco, Cristina Giugni, Manuela L’Erario and Zaccaria Ricci
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2023 3:10
    Content type: Original Article Published on:

  4. Trustworthy clinical practice guidelines represent a fundamental tool to summarize relevant evidence regarding a set of clinical choices and provide guidance for making optimal clinical decisions. Clinicians m...

    Authors: João Pedro Lima, Reza D. Mirza and Gordon H. Guyatt
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2023 3:9
    Content type: Review Published on:

  5. The following article presents the relevant and unprecedented bioethical and biolaw issues posed by the SARS-COV-2 pandemic and summarizes the initiatives adopted by the Italian Society of Anesthesia and Resus...

    Authors: Davide Mazzon, Mariassunta Piccinni, Anna Aprile, Alberto Grassetto, Silvia De Rosa, Fabio Baratto, Silvio Marafon, Fabio Toffoletto, Paolo Rosi and Paolo Navalesi
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2023 3:8
    Content type: Original Article Published on:

  6. Renal replacement therapies (RRT) are essential to support critically ill patients with severe acute kidney injury (AKI), providing control of solutes, fluid balance and acid–base status. To maintain the paten...

    Authors: Valentina Pistolesi, Santo Morabito, Vincenzo Pota, Fabrizio Valente, Francesca Di Mario, Enrico Fiaccadori, Giacomo Grasselli, Nicola Brienza, Vincenzo Cantaluppi, Silvia De Rosa, Vito Fanelli, Marco Fiorentino, Marita Marengo and Stefano Romagnoli
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2023 3:7
    Content type: Review Published on:

  7. Discriminating between virus-induced fever from superimposed bacterial infections is a common challenge in intensive care units. Superimposed bacterial infections can be detected in severe SARS-CoV2-infected p...

    Authors: Arianna Gatti, Paola Fassini, Antonino Mazzone, Stefano Rusconi, Bruno Brando and Giovanni Mistraletti
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2023 3:6
    Content type: Original Article Published on:

  8. The multiple modes of SARS-CoV-2 transmission including airborne, droplet, contact and faecal–oral transmissions that cause coronavirus disease 2019 (COVID-19) contribute to a public threat to the lives of peo...

    Authors: Erfei Zhang, Xiaoying Zhao, Xiaoyan An, Min Wang, Jie Gao, Hailiang Zhang and Ying Li
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2023 3:5
    Content type: Original Article Published on:

  9. Polymyxin B hemoperfusion (PMX) removes endotoxin from septic shock patients. Although the treatment has been clinically used for more than 20 years, its cost-effectiveness has not been evaluated in detail.

    Authors: Kenji Fujimori, Kunio Tarasawa and Kiyohide Fushimi
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2023 3:4
    Content type: Original Article Published on:

  10. Sepsis is marked by elevated histamine, which is a vasodilator that increases vascular permeability. Although human studies are lacking, murine models of sepsis have indicated potential protective effects of h...

    Authors: Tarek R. Firzli, Sunil Sathappan, Daniel Antwi-Amoabeng, Bryce D. Beutler, Mark B. Ulanja and Farah Madhani-Lovely
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2023 3:3
    Content type: Original Article Published on:

  11. In recent years, the relationship between the advantages and disadvantages of a deep neuromuscular block (DNMB), compared to a moderate block (MNMB) in laparoscopic surgery, has been increasingly studied.

    Authors: Antonio Coviello, Marilena Ianniello, Pasquale Buonanno, Nausica Di Falco, Carmine Iacovazzo, Alfredo Maresca, Maria Vargas, Annachiara Marra, Agostino Candice, Gabriele Saccone, Fulvio Zullo and Giuseppe Servillo
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2023 3:2
    Content type: Original Article Published on:

  12. Adult and pediatric palliative care (PC) share common aims and ethical principles but differ in many organizational and practical aspects. The aim of this narrative review is to analyze these differences and f...

    Authors: Cosimo Chelazzi, Gianluca Villa, Iacopo Lanini, Stefano Romagnoli and Nicola Latronico
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2023 3:1
    Content type: Review Published on:

  13. This consensus statement presents a comprehensive and evidence-based set of guidelines that modify the general European or US guidelines for hypotension management with vasopressors during cesarean delivery. I...

    Authors: Grace Anne B. Herbosa, Nguyen Ngoc Tho, Angelina A. Gapay, Suraphong Lorsomradee and Cong Quyet Thang
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2022 2:56
    Content type: Review Published on:

  14. Point-of-care ultrasound (POCUS) is an essential tool to assess and manage different pathologies in the intensive care unit, and many protocols have been proposed for its application in critical care literatur...

    Authors: Juliana Caldas, Carla Bittencourt Rynkowski and Chiara Robba
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2022 2:55
    Content type: Review Published on:

  15. We carry out a retrospective observational analysis of clinical records of patients with major placenta praevia who underwent cesarean section surgery over a period of 20 months in our hospital. Out of a total...

    Authors: Maria Loreto, Massimo Pisanti, Marco Celentani, Gilda Pasta, Alfredo Erman, Claudio Santangelo, Luca Gregorio Giaccari, Pasquale Sansone and Romolo Villani
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2022 2:54
    Content type: Original Article Published on:

  16. Studies on higher doses of sugammadex effect on QT interval and leading arrhythmia have been limited. In this study, we aimed to investigate possible proarrhythmic effect of higher doses of sugammadex in condi...

    Authors: Emin Tunç Demir and Mesut Erbaş
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2022 2:53
    Content type: Original Article Published on:

  17. Intellectually disabled (ID) patients present unique therapeutic challenges. We aimed to describe the characteristics of ID patients admitted to a general intensive care unit (ICU).

    Authors: Noa Bineth, Nevo Barel, Tali Bdolah-Abram, Philip Levin and Sharon Einav
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2022 2:52
    Content type: Original Article Published on:

  18. Multiple patient-related variables have been associated with reduced rates of survival to hospital discharge (SHD) after in-hospital cardiac arrest (IHCA). As opposed to most of these, anemia may be reversible...

    Authors: Lior Shor, Yigal Helviz and Sharon Einav
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2022 2:51
    Content type: Original Article Published on:

  20. Dexmedetomidine is a highly selective alpha-2 receptor agonist without any effect on the GABA receptor. It provides an excellent sedative and analgesic profile with few side effects. We report our experience w...

    Authors: Valerio Donatiello, Aniello Alfieri, Andrea Napolitano, Vincenzo Maffei, Francesco Coppolino, Vincenzo Pota, Maria Beatrice Passavanti, Maria Caterina Pace and Pasquale Sansone
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2022 2:49
    Content type: Original Article Published on:

  21. The leading cause of emergence delirium (ED) in children postoperatively is the exposure to inhalational anaesthetics. ED can occur immediately after waking from anaesthesia, making patients generally uncooper...

    Authors: Hind M. Alassaf, Amal M. Sobahi and Nasser S. Alshahrani
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2022 2:48
    Content type: Review Published on:

  22. In recent decades, there has been an increase in life expectancy in children with life-limiting conditions. Ideally, parents and clinicians would work together to ensure the best care for these children. Sever...

    Authors: Karen Mackintosh and Paul McConnell
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2022 2:47
    Content type: Review Published on:

  24. Levosimendan has been reported to have a positive effect on ischemia–reperfusion injury. Herein, we aimed to evaluate the effects of levosimendan applied after reperfusion in an experimental intestinal injury-...

    Authors: Hakan Aygun, Cimen Olguner, Ugur Koca, Bekir Ugur Ergur, Ali Rıza Sisman, Duyguhan Isguven, Pelin Girgin, Muhammed Akkus and Serkan Tulgar
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2022 2:45
    Content type: Original Article Published on:

  25. Critical care ultrasonography (US) is widely used by intensivists managing critically ill patients to accurately and rapidly assess different clinical scenarios, which include pneumothorax, pleural effusion, p...

    Authors: Antonio Messina, Chiara Robba, Rita Bertuetti, Daniele Biasucci, Francesco Corradi, Francesco Mojoli, Silvia Mongodi, Eduardo Rocca, Stefano Romagnoli, Filippo Sanfilippo, Luigi Vetrugno and Gianmaria Cammarota
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2022 2:44
    Content type: Review Published on:

  26. Colorectal cancer is quite common, and surgery is the most effective treatment for most patients. However, postoperative pain management is generally inadequate in most patients. This study aimed to determine ...

    Authors: Ozgenur Kekul, Yasemin Burcu Ustun, Cengiz Kaya, Esra Turunç, Burhan Dost, Sezgin Bilgin and Fatih Ozkan
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2022 2:43
    Content type: Original Article Published on:

  27. Since January 2020, coronavirus disease 19 (COVID-19) has rapidly spread all over the world. An early assessment of illness severity is crucial for the stratification of patients in order to address them to th...

    Authors: Michela Rauseo, Marco Perrini, Crescenzio Gallo, Lucia Mirabella, Karim Mariano, Giuseppe Ferrara, Filomena Santoro, Livio Tullo, Daniela La Bella, Paolo Vetuschi and Gilda Cinnella
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2022 2:42
    Content type: Original Article Published on:

  28. In polytrauma intensive care unit (ICU) patients, glutamine (GLN) becomes a “conditionally essential” amino acid; its role has been extensively studied in numerous clinical trials but their results are inconcl...

    Authors: Antonella Cotoia, Leonarda Pia Cantatore, Renata Beck, Livio Tullo, Donatella Fortarezza, Flavia Marchese, Giuseppe Ferrara and Gilda Cinnella
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2022 2:41
    Content type: Original Article Published on:

  29. The current organizational structure of the Italian healthcare system does not include the institutionalization of clinical ethics services.

    Authors: Matteo Filippini, Federico Nicoli, Mario Picozzi and Nicola Latronico
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2022 2:40
    Content type: Original Article Published on:

  30. Upper airway surgery often poses a challenge to both anesthesiologists and surgeons, as airway access, mechanical ventilation, and surgical difficulties may occur in a tricky combination. To fulfill the need f...

    Authors: Alberto Grassetto, Tommaso Pettenuzzo, Flavio Badii, Francesca Barzaghi, Riccardo Carlon, Sandro Dellarole, Marilena Pipitone, Alessandra Versaci, Nicolò Sella, Marco Lionello and Andy Bertolin
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2022 2:39
    Content type: Original Article Published on:

  31. The coronavirus disease 2019 (COVID-19) pandemic has caused over 530 million infections to date (June 2022), with a high percentage of intensive care unit (ICU) admissions. In this context, relatives have been...

    Authors: Filippo Sanfilippo, Luigi La Via, Giovanni Schembari, Francesco Tornitore, Gabriele Zuccaro, Alberto Morgana, Maria Rita Valenti, Francesco Oliveri, Federico Pappalardo and Marinella Astuto
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2022 2:38
    Content type: Original Article Published on:

  32. Krebs von den Lungen 6 (KL-6) is a high-molecular-weight mucin-like glycoprotein, which is also known as MUC1. KL-6 is mainly produced by type 2 pneumocytes and bronchial epithelial cells, and, therefore, elev...

    Authors: Giuliana Scarpati, Daniela Baldassarre, Massimo Boffardi, Vincenzo Calabrese, Edoardo De Robertis, Graziella Lacava, Filomena Oliva, Pasquale Pagliano, Gabriele Pascale, Giovanni L. Tripepi and Ornella Piazza
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2022 2:37
    Content type: Original Article Published on:

  33. COVID‑19 is a novel cause of acute respiratory distress syndrome (ARDS) that leads patients to intensive care unit (ICU) admission requiring invasive ventilation, who consequently are at risk of developing of ...

    Authors: Nardi Tetaj, Alessandro Capone, Giulia Valeria Stazi, Maria Cristina Marini, Gabriele Garotto, Donatella Busso, Silvana Scarcia, Ilaria Caravella, Manuela Macchione, Giada De Angelis, Rachele Di Lorenzo, Alessandro Carucci, Maria Vittoria Antonica, Ilaria Gaviano, Carlo Inversi, Elisabetta Agostini…
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2022 2:36
    Content type: Original Article Published on:

  34. Critically ill, COVID-19 patients are characterized by a hypermetabolic state and a reduced food intake and are at high risk of malnutrition and lean body mass loss. An appropriate metabolic-nutritional interv...

    Authors: Romano Tetamo, Ciro Fittipaldi, Salvatore Buono and Michele Umbrello
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2022 2:35
    Content type: Original Article Published on:

  35. Carbapenem-resistant Gram-negative bacteria are frequent causes of sepsis and septic shock in intensive care unit (ICU) and thus considered a public health threat. Until now, the best available therapies consi...

    Authors: Andrea Cortegiani, Giulia Ingoglia, Mariachiara Ippolito, Massimo Girardis, Marco Falcone, Federico Pea, Francesco Pugliese, Stefania Stefani, Pierluigi Viale and Antonino Giarratano
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2022 2:34
    Content type: Review Published on:

  36. Several perioperative factors are responsible for the dysregulation or suppression of the immune system with a possible impact on cancer cell growth and the development of new metastasis. These factors have th...

    Authors: Etrusca Brogi and Francesco Forfori
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2022 2:33
    Content type: Review Published on:

  37. Significant concerns raise for the healthcare workers involved in airway management of patients diagnosed with coronavirus 2019 disease (COVID-19).

    Authors: Gilberto Duarte-Medrano, Massimiliano Sorbello, Rafael Renato Susunaga-Hope, Paula Ivette Fuentes-Castro, Beatriz C. Avila-OrtIz, Aida Paola Velasco-Godinez, Wendy Y. Contreras-Garcia, Miguel Alejandro Pineda-Castillo, Felipe Urdaneta and Félix Ignacio Téllez-Ávila
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2022 2:32
    Content type: Original Article Published on:

  38. An amplified and/or prolonged surgical stress response might overcome the organs’ functional reserve, thus leading to postoperative complications. The aim of this systematic literature review is to underline h...

    Authors: Iacopo Lanini, Timothy Amass, Caterina Scirè Calabrisotto, Sergio Fabbri, Silvia Falsini, Chiara Adembri, Alessandro Di Filippo, Stefano Romagnoli and Gianluca Villa
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2022 2:31
    Content type: Review Published on:

  39. Authors: Michela Rauseo, Elena Spinelli, Nicolò Sella, Douglas Slobod, Savino Spadaro, Federico Longhini, Antonino Giarratano, Gilda Cinnella, Tommaso Mauri and Paolo Navalesi
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2022 2:30
    Content type: Correction Published on:

    The original article was published in Journal of Anesthesia, Analgesia and Critical Care 2022 2:28

  40. The appropriate timing of surgery and perioperative management of patients with previous SARS-CoV-2 infection are open issues. The purpose of this document is to support the clinical decision-making process re...

    Authors: Andrea Cortegiani, Vincenzo Francesco Tripodi, Carlo Alberto Castioni, Clelia Esposito, Nicola Galdieri, Roberta Monzani, Marco Rispoli, Alessandro Simonini, Vito Torrano, Antonino Giarratano and Angelo Gratarola
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2022 2:29
    Content type: Original Article Published on:

  41. Mechanical ventilation is a life-saving technology, but it can also inadvertently induce lung injury and increase morbidity and mortality. Currently, there is no easy method of assessing the impact that ventil...

    Authors: Michela Rauseo, Elena Spinelli, Nicolò Sella, Douglas Slobod, Savino Spadaro, Federico Longhini, Antonino Giarratano, Cinnella Gilda, Tommaso Mauri and Paolo Navalesi
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2022 2:28
    Content type: Review Published on:

    The Correction to this article has been published in Journal of Anesthesia, Analgesia and Critical Care 2022 2:30

  42. Endotoxin (ET) removal therapy with polymyxin B-immobilized fiber column hemoperfusion (PMX-HP) has been used for the treatment of septic shock. Some observational studies reported clinical benefits, particula...

    Authors: Hisataka Shoji and Ricard Ferrer
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2022 2:27
    Content type: Review Published on:

  43. Here, we describe the case of a 39-year-old woman with cystinosis who already suffered from an extra parenchymal pattern of restrictive lung disease and, after SARS-CoV-2-related respiratory failure, had a dif...

    Authors: Luigi Vetrugno, Valentina Angelini, Simone Antonio Smiraglia, Elisabetta Saraceni, Pierluigi Di Giannatale and Salvatore Maurizio Maggiore
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2022 2:26
    Content type: Letter to the Editor Published on:

  44. Endoscopic treatment for achalasia (POEM) is a recently introduced technique that incorporates the concepts of natural orifice transluminal surgery. Although pediatric achalasia is rare, POEM has been episodic...

    Authors: Fabio Sbaraglia, Pietro Familiari, Federica Maiellare, Marco Mecarello, Annamaria Scarano, Demetrio Del Prete, Rosa Lamacchia, Federica Antonicelli and Marco Rossi
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2022 2:25
    Content type: Original Article Published on:

  45. In order to systematically review the latest evidence on anesthesia, intraoperative neurologic monitoring, postoperative heparin reversal, and postoperative blood pressure management for carotid endarterectomy...

    Authors: Sergio Bevilacqua, Giulia Ticozzelli, Massimiliano Orso, Giuseppe Alba, Laura Capoccia, Alessandro Cappelli, Carlo Cernetti, Marina Diomedi, Walter Dorigo, Gianluca Faggioli, Giovanni Giannace, David Giannandrea, Matteo Giannetta, Gianfranco Lessiani, Enrico Maria Marone, Daniela Mazzaccaro…
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2022 2:24
    Content type: Original Article Published on:

  46. The ratio between arterial blood partial pressure of oxygen and fraction of inspired oxygen (PaO2/FiO2) was largely used for grading and managing the respiratory failure in non-mechanically ventilated COVID-19. I...

    Authors: Ilenia Gatto, Emanuela Biagioni, Irene Coloretti, Serena Viappiani, Stefano Busani and Massimo Girardis
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2022 2:23
    Content type: Brief Communication Published on:

  47. The use of extracorporeal carbon dioxide removal (ECCO2R) is less invasive than extracorporeal membrane oxygenation (ECMO), and intraoperative control of gas exchange could be feasible. The aim of this study in i...

    Authors: Franco Ruberto, Francesco Alessandri, Mario Piazzolla, Veronica Zullino, Katia Bruno, Paola Celli, Daniele Diso, Federico Venuta, Federico Bilotta and Francesco Pugliese
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2022 2:22
    Content type: Original Article Published on:

  48. Questions remain on the optimal management of subarachnoid hemorrhage (SAH) patients once they are admitted to the referring center, before and after the aneurysm treatment. To address these issues, we created...

    Authors: Edoardo Picetti, Andrea Barbanera, Claudio Bernucci, Alessandro Bertuccio, Federico Bilotta, Edoardo Pietro Boccardi, Tullio Cafiero, Anselmo Caricato, Carlo Alberto Castioni, Marco Cenzato, Arturo Chieregato, Giuseppe Citerio, Paolo Gritti, Luigi Lanterna, Roberto Menozzi, Marina Munari…
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2022 2:21
    Content type: Original Article Published on:

  49. Assess long-term quality of life (HR-QoL) and socio-economic impact in COVID-19-related ARDS (C-ARDS) survivors.

    Authors: Michele Umbrello, Sara Miori, Andrea Sanna, Sergio Lassola, Elena Baruzzo, Daniele Penzo, Giovanni Pedrotti, Annamaria Perino, Angelo Colombo, Rocco Pace and Sandra Magnoni
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2022 2:20
    Content type: Original Article Published on:

  50. Spinal anesthesia (SA) is widely used for anesthetic management of patients undergoing hip surgery, and hypotension is the most common cardiovascular side effect of SA. This paper aims to assess the lowest eff...

    Authors: Antonio Messina, Luigi La Via, Angelo Milani, Marzia Savi, Lorenzo Calabrò, Filippo Sanfilippo, Katerina Negri, Gianluca Castellani, Gianmaria Cammarota, Chiara Robba, Emanuela Morenghi, Marinella Astuto and Maurizio Cecconi
    Citation: Journal of Anesthesia, Analgesia and Critical Care 2022 2:19
    Content type: Review Published on:
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Journal of Anesthesia, Analgesia and Critical Care

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