Table 1 Comparison of demographic and clinical characteristics stratified by COVID-19 patients
Variablesa | overall (n= 14) | COVID-19 negative (n= 7) | COVID-19 positive (n= 7) | p-value |
|---|---|---|---|---|
Age, years | 65 (62-72) | 62 (62-69) | 72 (60-74) | 0.55 |
Males, n (%) | 9 (64.3) | 4 (57.1) | 5 (71.4) | 1.00 |
BMI, kg/m2 | 28.4 (25.6-29.4) | 27.5 (25.6-29.4) | 29.3 (24.5-29.4) | 0.83 |
APACHE II | 14.5 (10-20) | 19 (10-22) | 10 (10-18) | 0.19 |
SAPS II | 37 (34-50) | 45 (34-55) | 36 (34-38) | 0.33 |
Charlson Index | 3 (2-6) | 3 (2-4) | 5 (2-6) | 0.64 |
SOFA parameters at baseline | ||||
SOFA total score | 8.5 (6-9) | 9 (6-11) | 8 (5-9) | 0.24 |
GSC | 14.5 (14-15) | 14 (7-15) | 15 (14-15) | 0.48 |
PaO2/ FiO2 ratio | 121.5 (102-155) | 153 (102-202) | 107 (95-130) | 0.25 |
Mean arterial pressure, mm Hg | 73.5 (68-80) | 75 (65-80) | 72 (70-75) | 0.88 |
Creatine kinase, mg/dL | 0.75 (0.70-1.60) | 0.79 (0.67-4.2) | 0.70 (0.70-1.60) | 1.00 |
Platelet count, x 109 per L | 216 (147-272) | 180 (69-274) | 223 (209-272) | 0.25 |
Total bilirubin, mg/dL | 0.77 (0.46-0.90) | 0.80 (0.50-1.41) | 0.47 (0.40-0.80) | 0.13 |
Lung and Kidney | ||||
Compliance Rs, at baseline, cm H2O | 26.5 (20-32) | 27 (20-40) | 25 (18-29) | 0.40 |
Causes of lung injury | ||||
Pneumonia, n 12(%) Sepsis, n 2(%) Trauma, n 0(%) | 12 (85.7) 2 0 | 6 1 0 | 6 1 0 | |
KDIGO III, n (%) | 14 (100.0) | 7 (100.0) | 7 (100.0) | - |
Adjuvant therapy before ECCO2R | ||||
Neuromuscular blockade Prone positioning Nitric oxide Recruitment maneuvers | 14 (100.0) 6 (42.9) 0 14 (100.0) | 7 (100.0) 2 (28.6) 0 14 (100.0) | 7 (100.0) 4 (57.1) 0 14 (100.0) | |